Prospective Data Collection & Registries

As with the retrospective designs, prospective studies may be conducted to characterise and measure outcomes relating to disease epidemiology, treatment patterns, real-world safety and effectiveness, or burden of illness. The advantage to prospective studies is that they may minimise potential biases and missing data that can frequently occur in studies with retrospective designs. We have employed a variety of prospective techniques to estimate epidemiologic parameters, including through interviews, surveys or clinical data collection, amongst physicians, patient, or decision makers. We have used these techniques to estimate:

  • Prescribing behavior 
  • Treatment patterns
  • Adherence
  • Frequency of side effects 
  • Impact on health-related quality of life
  • Preferences

These methods apply to the design of studies focusing on measuring:

  • Burden of illness
    • Societal
    • Individual/humanistic 
    • Economic 
  • Real-world effectiveness and utilisation patterns