Economic Burden of Illness and Financial Impact Analysis

Cost-effectiveness analysis is increasingly central to reimbursement decision-making, whether formally by national and regional reimbursement authorities, or informally by decision-makers in private healthcare agencies.

Cost effectiveness analysis evaluates the costs and consequences of health interventions by employing decision analytic models to synthesise data derived from clinical trials, stand-alone studies, retrospective administrative database analyses, and systematic reviews of published literature. ICON is an international market leader in cost-effectiveness analysis. Our Health Economics team has a wealth of research and consulting expertise in economic evaluations, and utilises its scientific strengths alongside commercial and regulatory knowledge to achieve reliable and highly-credible results for our clients. 

Our team designs and builds economic models with the scientific rigor to powerfully and credibly communicate cost-effectiveness to national and regional reimbursement authorities and healthcare providers. Our models employ tried-and-tested, as well as state-of-the-art methods, including fully probabilistic analyses of uncertainty, value-of-information analyses and detailed sub-group analyses. We ensure quality control by conducting parallel programming for each model and by incorporating detailed analyses of assumptions, risk and uncertainty associated with study design and the state of knowledge surrounding data and values.